Guesdon b, denis rg, richard d 2010 additive effects of olanzapine and melanin-concentrating hormone agonism on energy balance.

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Patients may develop severe sedationcomaand or delirium after an injection of extended release olanzapinePatients must be examined for 3 hours after receiving an injection.

In patients whose manic episode has responded to olanzapine treatmentolanzapine is indicated for the prevention of recurrence in patients with bipolar disordersee section 5.1

Because clinical trials are conducted under widely varying conditionsadverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect or predict the rates observed in practice.

Keep out of reach of childrenIn case of overdoseget medical help or contact a Poison Control Center immediately.

There may be an increased risk of elevated blood sugar levels and diabetes with olanzapine as well as the other antipsychotic medications in its classPatients should be tested during treatment for elevated blood sugarAdditionallypersons with risk factors for diabetesincluding obesity or a family history of diabetesshould have their fasting levels of blood sugar tested before starting treatment and periodically throughout treatment to detect the onset of diabetesAny patient developing symptoms that suggest diabetes during treatment should be tested for diabetes.

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olanzapine and fluoxetine in combination also refer to the adverse reactions section of the package insert for symbyax.

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