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For the treatment of high blood pressureit may take 2 to 4 weeks before you get the full benefit of this medicationFor the treatment of heart failureit may take weeks to months before you get the full benefit of this medicationTell your doctor if your condition does not get better or if it gets worsefor exampleyour blood pressure readings remain high or increase

HypotensionSymptomatic hypotension has occurred after administration of lisinoprilusually after the first or second dose or when the dose was increasedIt is more likely to occur in patients who are volume depleted by diuretic therapydietary salt restrictiondialysisdiarrhea or vomiting or possibly in patients with renin-dependent renovascular hypertensionsee DosageIn patients with severe congestive heart failurewith or without associated renal insufficiencyexcessive hypotension has been observed and may be associated with oliguria and/or progressive azotemiaand rarely with acute renal failure and/or deathBecause of the potential fall in blood pressure in these patientstherapy should be started under very close medical supervisionusually in a hospitalSuch patients should be followed closely for the first 2 weeks of treatment and whenever the dose of lisinopril and/or diuretic is increasedSimilar considerations apply to patients with ischemic heart or cerebrovascular disease in whom an excessive fall in blood pressure could result in a myocardial infarction or cerebrovascular accidentsee Adverse Effects

It is not known whether lisinopril passes into breast milk or if it could harm a nursing babyYou should not breast-feed while using lisinopril.

The class of drugs called ACE inhibitors is commonly used for the treatment of elevated blood pressureThis class includes drugs such as ramiprilbrand nameAltacecaptoprilCapotenenalaprilVasotecfosinoprilMonoprillisinoprilPrinivilZestriland quinaprilAccuprilWe asked how much this class of drugs lowers blood pressure and whether there is a difference between individual drugs within the classThe available scientific literature was searched to find all the trials that had assessed this question.

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