Omeprazole; sodium bicarbonate moderate the plasma concentration of citalopram, a cyp2c19 substrate, may be increased when administered concurrently with omeprazole, a cyp2c19 inhibitor.

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dextromethorphan; promethazine major because of the potential risk and severity of serotonin syndrome, caution should be observed when coadministering drugs that have serotonergic properties such as dextromethorphan and citalopram.

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in vitro studies using human liver microsomes indicated that cyp3a4 and cyp2c19 are the primary isozymes involved in the n-demethylation of escitalopram.

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enalapril; hydrochlorothiazide, hctz moderate citalopram causes dose-dependent qt interval prolongation.

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although rare; eye swelling and redness have been reported in celexa citalopram use.

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