A study in the new england journal of medicine found that plavix-users are 12 times more likely to develop recurrent ulcers, gastrointestinal bleeding, and cerebral bleeding than a combination of aspirin and a heartburn medication.

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its much-anticipated anticoagulant drug eliquis, a warfarin alternative, isn t throwing up big numbers yet, but it has the potential to be the kind of blockbuster that plavix and avapro once were.

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while doctors long assumed that taking the anticlotting drug clopidogrel plavix along with aspirin provided additional coronary protection, a recent large clinical trial has shown that the combination works no better than aspirin alone and may increase the risk of harmful bleeding.

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