Patients should be informed that about a third of patients who have had hypersensitivity reactions to carbamazepine also experience hypersensitivity reactions with oxcarbazepine trileptal .
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a third trial substituted trileptal monotherapy at 2400 mg day for carbamazepine in 143 patients 12 to 65 years of age whose partial seizures were inadequately controlled on carbamazepine cbz monotherapy at a stable dose of 800 to 1600 mg day, and maintained this trileptal dose for 56 days baseline phase .
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clinically significant hyponatremia generally occurred during the first three months of treatment with trileptal, although there were patients who first developed a serum sodium 125 mmol l more than one year after initiation of therapy.
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