Bepridil moderate depression of av node conduction could be additive if cardiac glycosides, like digoxin, are used with bepridil.

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antiarrhythmics and proarrhythmic events have been observed by patients taking digoxin along with this drug.

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28 furthermore, a number of medications frequently prescribed to this patient population may directly interact with digoxin or impact digoxin levels indirectly via volume status changes, electrolyte imbalance, or drug elimination, 29 all of which can potentiate the risk of lethal tachy- and bradyarrhythmias e.

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recent observational data support an effect in acute poisoning, but efficacy in chronic poisoning be minimally effective in alleviating cardiac toxicities in chronic digoxin poisoning.

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