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azithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly haemophilus influenzae.

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hence, given that antibiotics are already considered the best options for he treatment and that the new drugs are still not useful in clinical practice, our proposal is very attractive because erythromycin is well known, easy to administer and less expensive than other treatments 23 .

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