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blood levels and or toxicity of propranolol may be increased by co-administration with substrates or inhibitors of cyp1a2, such as imipramine, cimetidine, ciprofloxacin, fluvoxamine, isoniazid, ritonavir, theophylline, zileuton, zolmitriptan, and rizatriptan.

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glycaemic control may be affected by diuretics, corticosteroids, phenothiazines, thyroid products, oestrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, calcium channel blockers, chlorpromazine and isoniazid.

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isoniazid serum concentrations decreased by 25 and 40 in slow and rapid acetylators, respectively, when isoniazid 10 mg kg was co-administered with another corticosteroid.

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