You might as well just prescribe clozaril, which has all these side effects plus agranulocytosis, but at least it is the only neuroleptic to soar above the pack in terms of efficacy, and is now the only psychiatric drug fda-approved for the prevention of suicide.
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since its introduction in 1990, clozaril has helped over 225,000 people with schizophrenia.
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in addition, clozaril very frequently causes a progressive movement disorder known as tardive dyskinesia, which involved involuntary facial movements including grimaces and tongue rolling.
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however, analysis of data from the clozaril national registry suggests that patients who have an initial episode of moderate leukopenia 3000 mm 3 wbc 2000 mm3 have up to a 12 -fold increased risk of having a subsequent episode of agranulocytosis when rechallenged compared to the full cohort of patients treated with clozaril clozapine .
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if you become pregnant while taking clozaril, do not stop taking it without your doctor s advice.
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this program makes sure that you will receive each refill of clozaril only if you have a blood test and your blood test result is acceptable to your healthcare provider.
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