Therefore, the conclusion that the suppressant effects of naltrexone on ethanol self-administration are the result of interference with ethanol-induced increases in extracellular dopamine in the nacc seems well justified.

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in clinical trials evaluating the effectiveness of naltrexone, patients who received naltrexone were twice as successful in remaining abstinent and in avoiding relapse as patients who received placebo-an inactive pill.

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naltrexone is an opiate receptor antagonist that blocks the pleasurable effects of alcohol and reduces cravings.


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