Severe reductions in blood pressure, especially when changing posture orthostatic hypotension , may occur when isosorbide mononitrate is combined with calcium channel blockers for example, diltiazem cardizem, dilacor, tiazac and several others , verapamil calan, verelan, verelan pm, isoptin, isoptin sr, covera-hs , which also reduce blood pressure.

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do not stop taking isoptin verapamil without first checking with your doctor.

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