Acetaminophen; dextromethorphan major agents which induce the hepatic isoenzyme cyp2e1, such as isoniazid, may potentially increase the risk for acetaminophen-induced hepatotoxicity via generation of a greater percentage of acetaminophen s hepatotoxic metabolites.

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vemurafenib major concomitant use of vemurafenib and isoniazid, inh may result in increased vemurafenib concentrations.

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sitagliptin minor although a rare side effect, isoniazid, inh may increase blood sugar.

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nervous system effects peripheral neuritis, usually preceded by paresthesia of the feet and hands, is the most common adverse effect of isoniazid and occurs most frequently in malnourished patients and those predisposed to.

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isoniazid, inh; pyrazinamide, pza; rifampin moderate a dose adjustment of budesonide may be necessary when administered concurrently with rifamycins, due to the potential for decreased exposure of budesonide.

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