If these symptoms appear or if signs suggestive of hepatic damage are detected, isoniazid should be discontinued promptly, since continued use of the drug in these cases has been reported to cause a more severe form of hepatotoxicity.
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alternatively, isoniazid and rifapentine may be administered once weekly to patients with pulmonary disease only.
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rifampin for 4 months was more cost-effective than isoniazid for 6 months.
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thus, the altered catalase-peroxidase provides high-level resistance to isoniazid, while retaining a level of oxidative protection that is sufficient to enable the organism to maintain detoxifying activity against host antibacterial radicals.
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don t breastfeed a baby while taking isoniazid without first talking to your physician.
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