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although an inadequate therapeutic response has been reported after intramuscular administration, 21 more studies in enteric fever have suggested that peak plasma chloramphenicol concentrations are not influenced significantly by the route of parenteral administration.
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chloramphenicol exerts its antibacterial effect by reversibly binding to bacterial ribosomes thereby inhibiting bacterial protein synthesis.
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if you have been given chloramphenicol eye ointment to use as well as the eye drops, apply the ointment at night only.
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