It is not recommended to use paroxetine in combination with metoprolol when given in cardiac insufficiency, because of the narrow therapeutic index of metoprolol in this indication.
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metabolized by cytochrome p450 2d6 increase antipsychotic levels toxicity risk monitor for toxicity clozapine fluoxetine paroxetine decrease antipsychotic levels lower efficacy barbiturates carbamazepine phenytoin rifampin other effects increased antihypertensive effect may result in hypotension raises prolactin levels avoid concurrent use of other medications prolonging qt interval see prolonged qt interval due to medication.
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a paroxetine is a medication that is used to treat depression, anxiety and panic disorders.
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