In another trial study 3 , 322 patients meeting dsm-iv criteria for major depressive disorder who had responded during an initial 10-week open-label treatment phase for about 25 days, on average, to emsam 6 mg per 24 hours were randomized either to continuation of emsam at the same dose n 159 or to placebo n 163 under double-blind conditions for observation of relapse.

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